If suitable, we can prescribe medicine for collection or to be delivered in discreet packaging in as little as two days. Grapefruit can increase the risk of experiencing side effects with Cialis or Cialis Daily. We recommend you avoid eating grapefruit or drinking grapefruit juice while you're taking this medicine and for a few days after you finish taking it.
What measures are being taken to ensure the safe and effective use of Cialis?
In these two studies, more patients had clinically significant decreases in blood pressure on the combination of tadalafil and alcohol as compared to alcohol alone. Some subjects reported postural dizziness, and orthostatic hypotension was observed in some subjects. In 1994, generic levitra comment here Pfizer scientists discovered that sildenafil, which also inhibits the PDE5 enzyme, caused penile erection in males participating in a clinical study of a heart medicine. Although ICOS scientists were not testing compound IC351 for treating ED, they recognized its potential usefulness for treating that disorder. Soon, in 1994, ICOS received a patent for compound IC351 (structurally unlike sildenafil and vardenafil), and Phase 1 clinical trials began in 1995. In 1997, the Phase 2 clinical studies were initiated for males experiencing ED, then progressed to the Phase 3 trials that supported the drug's FDA approval.
Yes, Cialis Super Active is available in South Africa with a valid prescription from a licensed healthcare provider or a registered online pharmacy. To explore more affordable options, you may consider purchasing Cialis Super Active through our trusted online platform. We partner with reliable global suppliers and ensure compliance with South Africa's import requirements.
Potential Side Effects
Cialis, or tadalafil, works by inhibiting the enzymе phosphodiesterase type 5 (PDE-5) in the body. This enzyme is responsible for breaking down a substance cаlled cyclic guаnosine monophоsphate (cGMP). CGMP is involved in the relaxation and dilation of blood vessels, including those in the penis.
In patients taking potent inhibitors ofCYP3A4 and CIALIS for once daily use, the maximum recommended dose is 2.5 mg [see DOSAGE AND ADMINISTRATION] . CIALIS for once daily use has not been extensively evaluated in patients with mild or moderate hepatic impairment. Therefore, caution is advised if CIALIS for once daily use is prescribed to these patients.
Unlike Viagra, Cialis is also approved to treat benign prostatic hyperplasia, which is enlargement of the prostate gland. Do not use this medicine if you are also using riociguat (Adempas®) or a nitrate medicine, often used to treat angina (chest pain). Nitrate medicines include nitroglycerin, isosorbide, Imdur®, Nitro-Bid®, Nitrostat®, Nitro-Dur®, Transderm Nitro®, Nitrol® Ointment, and Nitrolingual® Spray. Some illegal ("street") drugs called "poppers" (such as amyl nitrate, butyl nitrate, or nitrite) also contain nitrates. If you need to use a nitrate medicine, take it at least 48 hours after your last dose of tadalafil.
Other medical conditions you have can also affect your Cialis dosage. Buying Cialis Super Active through our online pharmacy is easy and secure. Your prescription is carefully handled, and all imports are fully aligned with South Africa's legal guidelines.
